TRÈSBIEN BioSynth Private Limited

Products For Poultry

Nanobiotechnology Range of Products

Innovative Mycotoxin Binder of European origin…..

Binary effect of inactivation of Zearalenone (Deoxynivalenol), Ochratoxin, Vomitoxin, Fumonisin, Aflatoxin, Citrinin & Trichothecenes (T-2 toxin) Toxin and Immune enhancement

A Broad spectrum in-feed Mycotoxin solution, with a special formulated combination of yeast products and Tribomechanically Activated Clinoptilolite (TMAZ) in a balanced ratio that provides an effective way of controlling mycotoxicosis through creation of multiple binding sites to absorb the range of threatening mycotoxins.

Mycotoxins Hidden threat to poultry feed Approx.50% of the worlds grain supply is contaminated with Mycotoxins (FAO, 2012)

How does ZOVFACT xpel work?
Tribomechanically activated Clinoptilolite (TMAZ) Particles smaller than 5 micron are taken up by M cells or Dendritic cells (DC) in intestinal wall. They are then transported to the lymph nodes where they stimulate B cells for improved antibody production.

Powerful negative charges (ion exchange power): “Remove heavy metals, DDI, dioxins, PCB’s, herbicides, radioactive particles and some viral particles from the body in a process known as cation exchange”. Particles smaller than 5 micron are taken up by M cells or Dendritic cells (DC) in intestinal wall. They are then transported to the lymph nodes where they stimulate B cells for improved antibody production.

Contains highly refined polysaccharide

complex derived from the cell wall of Saccharomyces cerevisiae yeast. Yeast also detoxifies many other Mycotoxins and successfully lessened the adverse consequences of aflatoxin and has no damaging effects. As some strains of Saccharomyces cerevisiae are good aflatoxin binders, these should be selected as starter cultures for respective fermented foods which can help to avoid potential health risk due to aflatoxin. Yeast showed ability to reverse the undesirable effects of aflatoxin on bird health, blood cells and immune system of birds.

Mannan Oligo Saccharides (MOS):

Mannan is present in the inner side of the cell wall of Saccharomyces cerevisiae, yeast which is glucan-rich. Yeast gluco-mannan showed high affinity for aflatoxins (75 to 90%) in vitro as well as in vivo and is widely used for detoxification of aflatoxins in poultry birds.
 Adhesion most important Pathogenic bacteria
 Adhesion mycotoxins ( Zearelenone, T-2 and
Deoxynivalenol)  Stimulation adaptive immunity similar to Clinoptilolite

Beta glucans:

Inclusion of purified yeast 𝛽-glucan have been shown to stimulate phagocytosis, bactericidal killing and oxidative burst in chickens.

Two Major Components of Immune System

Innate Immune Response
 Acquired Immune Response

𝛽-glucan works to activate both components of the immune system

In the Innate Immune system, 𝛽-glucan binds with macrophages, activates and increases their availability to identify and destroy foreign organism.

Working principle of Zovfact

Absorption:
Assimilation of molecular species throughout the bulk of the solid or liquid is termed as absorption. It is bulk phenomenon. Adsorption
Accumulation of the molecular species at the surface rather than in the bulk of the solid or liquid is termed as adsorption. It is a surface phenomenon.

Characteristics of an Ideal Mycotoxin Adsorbent

Ability to adsorb a wide range of mycotoxins
A low effective inclusion rate
Stability over a wide PH Range
High capacity to adsorb high concentrations of mycotoxins
High affinity to adsorb low concentrations of mycotoxins
Mycotoxins have direct bearing on egg shell quality
Mycotoxins reduced feed intake and egg production
Mycotoxins impact Antibody titer response
Mycotoxins impact immune organs such as Bursa & Thymus
Cysts developed on the peritoneal surface and within the oviduct. (Zearelenone mycotoxin)
Decreased comb and gonad weight

Usage and Administration: 0.5-2.5 Kg/MT of complete Feed. Or as specified by nutritionists or veterinarians.

 Mix into Feed according to the level of mycotoxin contamination

Physical Characteristics Colour - Beige Odour - Stable yeast aroma Purity - No foreign matter Appearance - Powder Shelf Life: 18 months from Date of Production.
Packing: 20 Kg Paper Bag with polyethylene liner.
Storage: Keep in cool, dry place, sealed and away from sunlight.

Additional information:

Saccharomyces cerevisiae live yeast was shown to reduce the detrimental effects of aflatoxin in broiler diets (Stanley et al., 1993).
A clinoptilolite was effective in reducing the effects of aflatoxin in quail (Parlat et al., 1999).

FEATURES

Bind wide range of mycotoxins
Low binding affnity for vitamins, minerals and other nutrients
Stable during processing and storage
Environmentally friendly after excretion.